A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell tolerance

Warshauer JT, Belk JA, Chan AY, Wang J, Gupta AR, Shi Q, Skartsis N, Peng Y, Phipps JD, Acenas D, Smith JA, Tamaki SJ, Tang Q, Gardner JM, Satpathy AT, Anderson MS.
J Exp Med, 11 June 2021

Repertoire Remodeling through CD4+ T-cell Depletion

Yao W, Satpathy AT.
Cancer Immunology Research, 10 June 2021

Identification of a T-bet hi Quiescent Exhausted CD8 T Cell Subpopulation That Can Differentiate into TIM3+ CX3CR1+ Effectors and Memory-like Cells

Raju S, Xia Y, Daniel B, Yost KE, Bradshaw E, Tonc E, Verbaro DJ, Kometani K, Yokoyama WM, Kurosaki T, Satpathy AT, Egawa T.
J Immunol, 4 June 2021

Differential usage of transcriptional repressor Zeb2 enhancers distinguishes adult and embryonic hematopoiesis

Huang X, Ferris ST, Kim S, Choudhary MNK, Belk JA, Fan C, Qi Y, Sudan R, Xia Y, Desai P, Chen J, Ly N, Shi Q, Bagadia P, Liu T, Guilliams M, Egawa T, Colonna M, Diamond MS, Murphy TL, Satpathy AT, Wang T, Murphy KM.
Immunity, 17 May 2021

Recruiting T cells in cancer immunotherapy

Yost KE, Chang HY, Satpathy AT.
Science, 9 April 2021

Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling

Weber EW, Parker KR, Sotillo E, Lynn RC, Anbunathan H, Lattin J, Good Z, Belk JA, Daniel B, Klysz D, Malipatlolla M, Xu P, Bashti M, Heitzeneder S, Labanieh L, Vandris P, Majzner RG, Qi Y, Sandor K, Chen LC, Prabhu S, Gentles AJ, Wandless TJ, Satpathy AT, Chang HY, Mackall CL.
Science, 2 April 2021

Interrogating immune cells and cancer with CRISPR-Cas9

Buquicchio FA, Satpathy AT.
Trends in Immunology, 31 March 2021

B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells

Yu B, Qi Y, Li R, Shi Q, Satpathy A, Chang HY.
Cell, 17 March 2021

Surface proteomics reveals CD72 as a target for in vitro-evolved nanobody-based CAR-T cells in KMT2A/MLL1-rearranged B-ALL

Nix MA, Mandal K, Geng H, Paranjape N, Lin YT, Rivera J, Marcoulis M, White KL, Whitman JD, Bapat SP, Parker KR, Ramirez J, Deucher A, Phojanokong P, Steri V, Fattahi F, Hann B, Satpathy AT, Manglik A, Stieglitz E, Wiita AP.
Cancer Discovery, 16 March 2021