Erythropoietin receptor on cDC1s dictates immune tolerance
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Nature, 10 December 2025
FOXP3 expression depends on cell-type-specific cis-regulatory elements and transcription factor circuitry
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Immunity, 13 November 2025
Engineering T cells with a membrane-tethered version of SLP-76 overcomes antigen-low resistance to CAR T cell therapy
Maria Caterina Rotiroti; Aidan M Tousley; Hoyin Chu; Marco Herrera-Barrera; Antigoni Manousopoulou; Won-Ju Kim; Yajie Yin; Thomas Spencer Parish; Aniela Mitchell; Malcolm Holterhus; Lea Wenting Rysavy; Guillermo Nicolas Dalton; Katherine Ann Freitas; Gernot Kaber; Korbinian N Kropp; Christopher A Klebanoff; Ansuman T Satpathy; Leo D Wang; Caleb A Lareau; Robbie G Majzner
Nature Cancer, 23 October 2025
The transcriptional repressor BLIMP1 enforces TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells
Maegan K Murphy, Matthew McCullen, Joshua L Deffenbaugh, Andy Y Chen, Joy Pai, Bence Daniel, Amir Yousif, Saravanan Raju, Sunnie Hsiung, Zhenxiao Wang, Hazem E Ghoneim, Ansuman T Satpathy, Marco Colonna, Eugene M Oltz, Takeshi Egawa
Immunity, 14 October 2025
Cell type-specific purifying selection of synonymous mitochondrial DNA variation
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PNAS, 29 July 2025
Massively parallel immunopeptidome by DNA sequencing provides insights into cancer antigen presentation
Quanming Shi, Elana P Simon, Cansu Cimen Bozkus, Anna Kaminska, Leandra Velazquez, Mansi Saxena, Zilin Zhang, Julia A Belk, Shuo Wang, Nuoya Yang, Yaowen Zhang, Ashley Kwong, Yonglu Che, Robert R Stickels, Charles R Crain, Laura Schmidt-Hong, Cheryl F Lichti, Gaurav D Gaiha, Theodore L Roth, Nina Bhardwaj, Ansuman T Satpathy, Bingfei Yu, Howard Y Chang
Nature Genetics, 28 July 2025
Clonal tracing with somatic epimutations reveals dynamics of blood ageing
Michael Scherer, Indranil Singh, Martina Maria Braun, Chelsea Szu-Tu, Pedro Sanchez Sanchez, Dominik Lindenhofer, Niels Asger Jakobsen, Verena Körber, Michael Kardorff, Lena Nitsch, Pauline Kautz, Julia Rühle, Agostina Bianchi, Luca Cozzuto, Robert Frömel, Sergi Beneyto-Calabuig, Caleb Lareau, Ansuman T Satpathy, Renée Beekman, Lars M Steinmetz, Simon Raffel, Leif S Ludwig, Paresh Vyas, Alejo Rodriguez-Fraticelli, Lars Velten
Nature, 21 May 2025
Translation dysregulation in cancer as a source for targetable antigens
Chen Weller, Osnat Bartok, Christopher S McGinnis, Heyilimu Palashati, Tian-Gen Chang, Dmitry Malko, Merav D Shmueli, Asuteka Nagao, Deborah Hayoun, Ayaka Murayama, Yuriko Sakaguchi, Panagiotis Poulis, Aseel Khatib, Bracha Erlanger Avigdor, Sagi Gordon, Sapir Cohen Shvefel, Marie J Zemanek, Morten M Nielsen, Sigalit Boura-Halfon, Shira Sagie, Nofar Gumpert, Weiwen Yang, Dmitry Alexeev, Pelgia Kyriakidou, Winnie Yao, Mirie Zerbib, Polina Greenberg, Gil Benedek, Kevin Litchfield, Ekaterina Petrovich-Kopitman, Adi Nagler, Roni Oren, Shifra Ben-Dor, Yishai Levin, Yitzhak Pilpel, Marina Rodnina, Jürgen Cox, Yifat Merbl, Ansuman T Satpathy, Yaron Carmi, Florian Erhard, Tsutomu Suzuki, Allen R Buskirk, Johanna Olweus, Eytan Ruppin, Andreas Schlosser, Yardena Samuels
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Non-viral intron knock-ins for targeted gene integration into human T cells and for T-cell selection
Theodore L Roth, Johnathan Lu, Alison McClellan, Courtney Kernick, Oliver Takacsi-Nagy, Ansuman T Satpathy
Nature Biomedical Engineering, 7 March 2025
Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing
Tsion Abay, Robert R. Stickels, Meril T. Takizawa, Benan N. Nalbant, Yu-Hsin Hsieh, Sidney Hwang, Catherine Snopkowski, Kenny Kwok Hei Yu, Zaki Abou-Mrad, Viviane Tabar, Brooke E. Howitt, Leif S. Ludwig, Ronan Chaligné, Ansuman T. Satpathy & Caleb A. Lareau
Nature Genetics, 8 January 2025