Regulation of immune signal integration and memory by inflammation-induced chromosome conformation
Daniel B; Chen AY; Sandor K; Zhang W; Miao Z; Yost KE; Lareau CA; Chang HY; Satpathy AT
PNAS, 15 September 2026
Comparing bulk and single-cell methodologies and models to profile gene expression, chromatin accessibility and regulatory links in endothelial cells treated with TNFα
Zevounou J; Lo KS; McGinnis CS; Satpathy AT; Lettre G
Biochemistry and Biophysics Reports, 9 September 2026
Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits
Zhu R; Dann E; Yan J; Reyes Retana J; Goto R; Guitche RC; Brixi L; Ota M; Hartman A; Roth TL; Satpathy AT; Pritchard JK; Marson A
Cell, 28 August 2026
Synthetic transcription factors designed by domain recombination enhance CAR T cell antitumor function
Takacsi-Nagy O; Kasinathan S; Hartman A; Yin Y; Wu L; Chen AY; Moser LM; May AP; Reeder GC; Celallos Fuentes E; Kernick C; Lu J; McClellan AK; Raposo CJ; Terrall B; Theberath NE; Yan PK; Xu P; Sotillo E; Eyquem J; Mackall CL; Roth TL; Satpathy AT
Cell, 19 August 2026
Mapping enhancer-gene regulatory interactions from single-cell data
Sheth MU; Qiu WL; Ma XR; Gschwind AR; Jagoda E; Tan AS; Galante J; Ray J; Amgalan D; Einarsson H; Gorissen BL; Dubocanin D; McGinnis CS; Huang J; Munson G; Brand K; Satpathy AT; Jones TR; Steinmetz LM; Kundaje A; Ustun B; Engreitz JM; Andersson R
Nature Genetics, 3 August 2026
Clonal lineage tracing of innate immune cells in human cancer
Liu V; Sandor K; Yan PK; Miao Z; Yin Y; Stickels RR; Chen AY; Hiam-Galvez K; Gutierrez J; Zhang W; Sajjath SM; Valbuena R; Wang S; Daniel B; Ludwig LS; Howitt BE; Lareau CA; Satpathy AT
Cancer Cell, 4 June 2026
In vivo site-specific engineering to reprogram T cells
Nyberg WA; Bernard PL; Ngo W; Wang CH; Ark J; Rothrock A; Borgo GM; Kimmerly GR; Jung JH; Allain V; Hamilton JR; Baldwin A; Stickels R; Wyman S; Khan SH; Lang S; Marsh D; Almudhfar N; Novick C; Mortazavi Y; Zhang S; AbdElwakil MM; Sandoval LR; Hwang S; Chu SN; Jung H; Liu C; Sharma D; McCreary T; Li Z; Satpathy AT; Carnevale J; Rutishauser RL; Cromer MK; Roybal KT; Dodgson SE; Doudna JA; Asokan A; Eyquem J
Nature, 18 March 2026
FOXP3 expression depends on cell-type-specific cis-regulatory elements and transcription factor circuitry
Jennifer M Umhoefer; Maya M Arce; Sivakanthan Kasinathan; Sean Whalen; Rama Dajani; Sanjana Subramanya; Laine Goudy; Julia A Belk; Royce Zhou; Minh T N Pham; Wenxi Zhang; Rosmely Hernandez; Carinna Tran; Nikhita Kirthivasan; Jacob W Freimer; Cody T Mowery; Vinh Nguyen; Mineto Ota; Benjamin G Gowen; Dimitre R Simeonov; Gemma L Curie; Zhongmei Li; Andy Y Chen; Jacob E Corn; Howard Y Chang; Qizhi Tang; Luke A Gilbert; Ansuman T Satpathy; Katherine S Pollard; Alexander Marson
Immunity, 13 January 2026