Interrogation of human hematopoiesis at single-cell and single-variant resolution

Ulirsch JC*, Lareau CA*, Bao EL*, Ludwig LS, Guo MH, Benner C, Satpathy AT, Salem R, Hirschhorn JN, Finucane HK, Aryee MJ, Buenrostro JD*, Sankaran VG*.
Nature Genetics, 11 March 2019

A mutation in the transcription factor Foxp3 drives T helper 2 effector function in regulatory T cells

Van Gool F, Nguyen MLT, Mumbach MR, Satpathy AT, Rosenthal WL, Giacometti S, Le DT, Liu W, Brusko TM, Anderson MS, Rudensky AY, Marson A, Chang HY, Bluestone JA.
Immunity, 19 February 2019

Pembrolizumab for advanced basal cell carcinoma: an investigator-initiated, proof-of-concept study

Chang ALS, Tran DC, Cannon JGD, Li S, Jeng M, Patel R, Van der Bokke L, Pague A, Brotherton R, Rieger KE, Satpathy AT, Yost KE, Reddy S, Sarin K, Colevas AD.
Journal of the American Academy of Dermatology, 1 February 2019

Coupled single-cell CRISPR screening and epigenomic profiling reveals causal gene regulatory networks

Rubin AJ*, Parker KR*, Satpathy AT*, Qi Y, Wu B, Ong AJ, Mumbach MR, Ji AL, Kim DS, Cho SW, Zarnegar BJ, Greenleaf WJ, Chang HY*, Khavari PA*.
Cell, 10 January 2019

The chromatin accessibility landscape of primary human cancers

Corces MR*, Granja JM*, Shams S, Louie BH, Seoane JA, Zhou W, Silva TC, Greoneveld C, Wong CK, Cho SW, Satpathy AT, Mumbach MR, Hoadley KA, Robertson AG, Sheffield NC, Felau I, Castro MAA, Berman BP, Staudt LM, Zenklusen JC, Laird PW, Curtis C, TCGA, Greenleaf WJ*, Chang HY*.
Science, 26 October 2018

Notch2-dependent DC2s mediate splenic germinal center responses

Briseno CG, Satpathy AT, Davidson JT, Ferris ST, Dura V, Bagadia P, O’Connor KW, Theisen DJ, Murphy TL, Murphy KM.
PNAS, 16 October 2018

Enhancer connectome nominates target genes of inherited risk variants from inflammatory skin disorders

Jeng MY, Mumbach MR, Granja JM, Satpathy AT, Chang HY, Chang ALS.
Journal of Investigative Dermatology, 10 October 2018

Expression of the transcription factor ZBTB46 distinguishes human histiocytic disorders of classical dendritic cell origin

Satpathy AT*#, Brown RA*, Gomulia E, Briseno CG, Mumbach MR, Pan Z, Murphy KM, Natkunam Y, Chang HY, Kim J. *contributed equally, #corresponding author
Modern Pathology, 1 September 2018

Integrative analysis of single-cell genomics data by coupled nonnegative matrix factorizations

Duren Z*, Chen X*, Zamanighomi M*, Zeng W, Satpathy AT, Chang HY, Wang Y, Wong W.
PNAS, 24 July 2018

Transcript-indexed ATAC-seq for precision immune profiling

Satpathy AT*, Saligrama N*, Buenrostro JD*, Wei Y, Wu B, Rubin AJ, Granja JM, Li R, Mumbach MR, Lareau CA, Serratelli WS, Gennert DG, Schep AN, Corces MR, Kim YH, Khavari PA, Greenleaf WJ, Davis MM*, Chang HY*. *contributed equally
Nature Medicine, 1 May 2018