Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche
Daniel Haensel, Bence Daniel, Sadhana Gaddam, Cory Pan, Tania Fabo, Jeremy Bjelajac, Anna R Jussila, Fernanda Gonzalez, Nancy Yanzhe Li, Yun Chen, JinChao Hou, Tiffany Patel, Sumaira Aasi, Ansuman T Satpathy, Anthony E Oro
Nature Communications, 10 May 2023
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis
Joshua S. Weinstock, Jayakrishnan Gopakumar, Bala Bharathi Burugula, Md Mesbah Uddin, Nikolaus Jahn, Julia A. Belk, Hind Bouzid, Bence Daniel, Zhuang Miao, Nghi Ly, Taralynn M. Mack, Sofia E. Luna, Katherine P. Prothro, Shaneice R. Mitchell, Cecelia A. Laurie, Jai G. Broome, Kent D. Taylor, Xiuqing Guo, Moritz F. Sinner, Aenne S. von Falkenhausen, Stefan Kääb, Alan R. Shuldiner, Jeffrey R. O’Connell, Joshua P. Lewis, Eric Boerwinkle, Kathleen C. Barnes, Nathalie Chami, Eimear E. Kenny, Ruth J. F. Loos, Myriam Fornage, Lifang Hou, Donald M. Lloyd-Jones, Susan Redline, Brian E. Cade, Bruce M. Psaty, Joshua C. Bis, Jennifer A. Brody, Edwin K. Silverman, Jeong H. Yun, Dandi Qiao, Nicholette D. Palmer, Barry I. Freedman, Donald W. Bowden, Michael H. Cho, Dawn L. DeMeo, Ramachandran S. Vasan, Lisa R. Yanek, Lewis C. Becker, Sharon L. R. Kardia, Patricia A. Peyser, Jiang He, Michiel Rienstra, Pim Van der Harst, Robert Kaplan, Susan R. Heckbert, Nicholas L. Smith, Kerri L. Wiggins, Donna K. Arnett, Marguerite R. Irvin, Hemant Tiwari, Michael J. Cutler, Stacey Knight, J. Brent Muhlestein, Adolfo Correa, Laura M. Raffield, Yan Gao, Mariza de Andrade, Jerome I. Rotter, Stephen S. Rich, Russell P. Tracy, Barbara A. Konkle, Jill M. Johnsen, Marsha M. Wheeler, J. Gustav Smith, Olle Melander, Peter M. Nilsson, Brian S. Custer, Ravindranath Duggirala, Joanne E. Curran, John Blangero, Stephen McGarvey, L. Keoki Williams, Shujie Xiao, Mao Yang, C. Charles Gu, Yii-Der Ida Chen, Wen-Jane Lee, Gregory M. Marcus, John P. Kane, Clive R. Pullinger, M. Benjamin Shoemaker, Dawood Darbar, Dan M. Roden, Christine Albert, Charles Kooperberg, Ying Zhou, JoAnn E. Manson, Pinkal Desai, Andrew D. Johnson, Rasika A. Mathias, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Thomas W. Blackwell, Goncalo R. Abecasis, Albert V. Smith, Hyun M. Kang, Ansuman T. Satpathy, Pradeep Natarajan, Jacob O. Kitzman, Eric A. Whitsel, Alexander P. Reiner, Alexander G. Bick & Siddhartha Jaiswal
Nature, 12 April 2023
Lineage tracing reveals clonal progenitors and long-
term persistence of tumor-specific T cells during
immune checkpoint blockade
Joy A. Pai, Matthew D. Hellmann, Jennifer L. Sauter, Marissa Mattar, Hira Rizvi, Hyung Jun Woo, Nisargbhai Shah, Evelyn M. Nguyen, Fathema Z. Uddin, Alvaro Quintanal-Villalonga, Joseph M. Chan, Parvathy Manoj, Viola Allaj, Marina K. Baine, Umesh K. Bhanot, Mala Jain, Irina Linkov, Fanli Meng, David Brown, Jamie E. Chaft, Ansuman T. Satpathy
Cancer Cell, 30 March 2023
Cis interactions in the Irf8 locus regulate stage-dependent enhancer activation
Tian-Tian Liu, Feiya Ou, Julia A Belk, Prachi Bagadia, David A Anderson 3rd, Vivek Durai, Winnie Yao, Ansuman T Satpathy, Theresa L Murphy, Kenneth M Murphy
Genes & Development, 23 March 2023
Co-opting signalling molecules enables logic-gated control of CAR T cells
Aidan M Tousley, Maria Caterina Rotiroti, Louai Labanieh, Lea Wenting Rysavy, Won-Ju Kim, Caleb Lareau, Elena Sotillo, Evan W Weber, Skyler P Rietberg, Guillermo Nicolas Dalton, Yajie Yin, Dorota Klysz, Peng Xu, Eva L de la Serna, Alexander R Dunn, Ansuman T Satpathy, Crystal L Mackall, Robbie G Majzner
Nature, 8 March 2023
Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility
Caleb A Lareau, Vincent Liu, Christoph Muus, Samantha D Praktiknjo, Lena Nitsch, Pauline Kautz, Katalin Sandor, Yajie Yin, Jacob C Gutierrez, Karin Pelka, Ansuman T Satpathy, Aviv Regev, Vijay G Sankaran, Leif S Ludwig
Nature Protocols, 15 February 2023
A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages
Simone Brioschi, Julia A Belk, Vincent Peng, Martina Molgora, Patrick Fernandes Rodrigues, Khai M Nguyen, Shoutang Wang, Siling Du, Wei-Le Wang, Gary E Grajales-Reyes, Jennifer M Ponce, Carla M Yuede, Qingyun Li, John M Baer, David G DeNardo, Susan Gilfillan, Marina Cella, Ansuman T Satpathy, Marco Colonna
Immunity, 14 February 2023
Reinfection with SARS-CoV-2 and Waning Humoral Immunity: A Case Report
Jason D. Goldman, Kai Wang, Katharina Röltgen, Sandra C. A. Nielsen, Jared C. Roach,* ,
Samia N. Naccache, Fan Yang, Oliver F. Wirz, Kathryn E. Yost, Ji-Yeun Lee, Kelly Chun, Terri Wrin,
Christos J. Petropoulos, Inyoul Lee, Shannon Fallen, Paula M. Manner, Julie A. Wallick, Heather A. Algren, Kim M. Murray, Jennifer Hadlock, Daniel Chen, Chengzhen L. Dai, Dan Yuan,
Yapeng Su, Joshua Jeharajah, William R. Berrington, George P. Pappas, Sonam T. Nyatsatsang,
Alexander L. Greninger, Ansuman T. Satpathy, John S. Pauk, Scott D. Boyd, and James R. Heath
Vaccines, 20 December 2022
Macrophage inflammatory and regenerative response periodicity is programmed by cell cycle and chromatin state
BenceDaniel, Julia A.Belk, Stefanie L.Meier, Andy Y.Chen, Katalin Sandor, ZsoltCzimmerer, ZsofiaVarga, Krisztian Bene, Frank A.Buquicchio, YanyanQi, Hugo Kitano, Joshua R. Wheeler, Deshka S. Foster, Michael Januszyk, Michael T. Longaker, Howard Y. Chang, Ansuman T. Satpathy
Molecular Cell, 14 December 2022
Engineered cell entry links receptor biology with single-cell genomics
Bingfei Yu, Quanming Shi, Julia A. Belk, Kathryn E. Yost, Kevin R. Parker, Rui Li,Betty B. Liu, Huang Huang,
Daniel Lingwood, William J. Greenleaf, Mark M. Davis, Ansuman T. Satpathy, and Howard Y. Chang
Cell, 13 December 2022